Drug Information

Klisyri

What is KLISYRI?

(KLISYRI) This medication is used to treat a certain skin condition (actinic keratosis) on the face or scalp area.

How should I use KLISYRI?

Read the Patient Information Leaflet if available from your pharmacist before you start using tirbanibulin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Use this medication on the skin only. Wash and dry your hands before applying the medication. Apply enough medication to cover the affected skin on the face or scalp as directed by your doctor, usually once a day for 5 days in a row. Use a new packet for each application. Wash your hands with soap and water after using to avoid getting the medication in your eyes or on other areas of your body. Do not cover the treated area with bandages or other dressings. Avoid washing or touching the treated area for about 8 hours after applying the medication. After about 8 hours, you may then wash the area with water and a mild soap. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Do not apply the medication in or around the eyes or mouth or on any damaged skin or skin that is healing. If you do get the medication in those areas, flush with plenty of water. Get medical help right away if the medication gets into your eyes. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Tell your doctor if your condition lasts or gets worse.

What should I tell my health care provider before I take KLISYRI?

Before using tirbanibulin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your condition may get worse when exposed to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Wear protective clothing when outdoors. Ask your doctor if you should use sunscreen along with this medication. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What may interact with KLISYRI?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

What if I miss a dose of KLISYRI?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

What side effects may I notice from receiving KLISYRI?

Swelling, scaling/flaking, pain, itching, or redness at the application site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: pus/blister/ulcer at application site. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Where should I keep KLISYRI?

Store at room temperature. Do not refrigerate or freeze. Discard the opened packet after each use. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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